COMPLETING THE BASEL PHAGE COLLECTION TO UNLOCK HIDDEN DIVERSITY FOR SYSTEMATIC EXPLORATION OF PHAGE-HOST INTERACTIONS.

Completing the BASEL phage collection to unlock hidden diversity for systematic exploration of phage-host interactions.

Research on bacteriophages, the viruses infecting bacteria, has fueled the development of modern molecular biology and inspired their therapeutic application to combat bacterial multidrug resistance.However, most work has so far focused on a few model phages which impedes direct applications of these findings in clinics and suggests that a vast pot

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A case of surgically treated non-metastatic SMARCA4-deficient undifferentiated thoracic tumor: a case report and literature review

SMARCA4-deficient undifferentiated thoracic tumor (SMARCA4-UT) is a rare malignant tumor characterized by inactivation of the SMARCA4 gene and the presence of undifferentiated or rhabdoid morphology in the Medium Oblong Platter tissue.This tumor is highly invasive, typically diagnosed at advanced stages III or IV, and commonly involves thoracic str

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Robustaflavone Isolated from Nandina domestica Using Bioactivity-Guided Fractionation Downregulates Inflammatory Mediators

Nandina domestica (Berberidaceae) has been used in traditional medicine for the treatment of cough.This plant is distributed in Korea, Japan, China, and India This study aimed to investigate the anti-inflammatory phytochemicals obtained from the N.domestica fruits.We isolated a biflavonoid-type phytochemical, robustaflavone (R), from N.domestica fr

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